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Hi James,

I would first recommend at least the following use flags:

accessibility alsa portaudio

For software speech, after you have the kernel configured, compiled and
installed, while you are in the croot, give this command:

emerge espeakup

That will install the espeakup connector and speakup.

Then, add this line to /etc/modules.autoload.d/kernel-2.6:

speakup_soft

Then, give this command:

rc-update add espeakup default

That will set espeakup to start automatically.

Let me know if you have any questions.

Thanks,

- -- 
William Hubbs
gentoo accessibility team lead
williamh@g.o
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